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Study Ref. Design studied treatmentcontrol treatmentpatientsstudy risk of biassample sizes Results

COVID 19 outpatients meta-analysis

PINETREE (GS-US-540-9012), 2021
 
NCT04501952
RCTremdesivirplaceboCOVID 19 outpatientslow
292/292 conclusif
  • demonstrated 87 % decrease in hospitalization or death (PE) with a high degree of certainty due to low risk of bias
  • suggested 72 % decrease in hospitalization with a high degree of certainty due to low risk of bias

PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).