remdesivir for COVID-19: living meta-analysis of clinical studies

Study explorer (study characteristics and results) method abbreviations pdf xlsx

display ongoing studies
Study	Ref.	Design	studied treatment	control treatment	patients	study risk of bias	sample sizes	Results	deaths E	clinical improvement E	death or ventilation E
COVID 19 hospitalized meta-analysis
DisCoVeRy (remdesivir) NCT04315948		RCT	remdesivir	standard of care	COVID 19 hospitalized	some concern	429/428	no results
Mahajan		RCT	remdesivir	standard of care	COVID 19 hospitalized	some concern	41/41	inconclusive
SOLIDARITY (remdesivir) NCT04315948		RCT	remdesivir	standard of care	COVID 19 hospitalized	some concern	2750/2725	inconclusive
COVID 19 all comers meta-analysis
Norwegian NOR study (remdesivir) NCT04321616		RCT	remdesivir	standard of care	COVID 19 all comers	some concern	43/58	no results
COVID-19 mild to moderate meta-analysis
GS-US-540-5774, 10 days NCT04292730		RCT	remdesivir	standard of care	COVID-19 mild to moderate	some concern	197/200	safety concern
GS-US-540-5774, 5 days NCT04292730		RCT	remdesivir	standard of care	COVID-19 mild to moderate	some concern	199/200	conclusif

PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).

Study explorer (study characteristics and results) method abbreviations pdf xlsx

COVID 19 hospitalized meta-analysis

COVID 19 all comers meta-analysis

COVID-19 mild to moderate meta-analysis