Study explorer (study characteristics and results) method abbreviations pdf   xlsx

display ongoing studies
Study Ref. Design studied treatmentcontrol treatmentpatientsstudy risk of biassample sizes Results

COVID-19 severe or critically meta-analysis

COVID STEROID 2
  NCT04509973		 RCTDexamethasone 12mgdexamethasone 6mgCOVID-19 severe or criticallylow
497/485 inconclusive
    Jamaati
          IRCT20151227025726N1    		 RCTdexamethasonestandard of careCOVID-19 severe or criticallysome concern
    		25/25 suggested
    • inconclusive 19 % increase in deaths,death D28 (PE) with a moderate degree of certainty due to some concern in risk of bias
    • inconclusive 38 % increase in mechanical ventilation (PE) with a moderate degree of certainty due to some concern in risk of bias
    • suggested 3.9-fold increase in radiologic improvement (14-day) with a moderate degree of certainty due to some concern in risk of bias
    CODEX (Tomazini)
          NCT04327401    		 RCTdexamethasonestandard of careCOVID-19 severe or criticallysome concern
    		151/148 inconclusive
      DEXA-COVID19
              NCT04325061      		 RCTdexamethasonestandard of careCOVID-19 severe or criticallylow
      		7/12 inconclusive
        1 study excluded by filtering options (1 RCT / 0 OBS)

        PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
        Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).

         

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