Study explorer (study characteristics and results) method abbreviations pdf   xlsx

display ongoing studies
Study Ref. Design studied treatmentcontrol treatmentpatientsstudy risk of biassample sizes Results

COVID-19 (hospitalized or not) meta-analysis

Luxenburger OBSproton pump inhibitors (PPI)controlCOVID-19 (hospitalized or not)critical
62/90 safety concern
  • statistically significant 3.1-fold increase in deaths but with a very low degree of certainty due to critical risk of bias
  • statistically significant 1.7-fold increase in clinical deterioration but with a very low degree of certainty due to critical risk of bias
  • statistically significant 1.4-fold increase in superinfection but with a very low degree of certainty due to critical risk of bias
Ullah (Confirmed) OBSproton pump inhibitors (PPI)controlCOVID-19 (hospitalized or not)NA
87/103 inconclusive
    Lee (confirmed COVID-19) OBSproton pump inhibitors (PPI)controlCOVID-19 (hospitalized or not)critical
    		267/267 safety concern
    • statistically significant 79 % increase in death or transfer to ICU but with a very low degree of certainty due to critical risk of bias
    • statistically significant 63 % increase in death or ventilation but with a very low degree of certainty due to critical risk of bias

    PE: primary endpoint; (a): to be demonstrated a result must be statistically significant on a primary endpoint (with multiplicity adjustment if necessary);
    Study risk of bias assessed for the study primary endpoint(s) or the main endpoints in case of no formally defined primary endpoint(s).

     

    - About us - Contact us - Method - RSS Made with in Lyon - Credits - Privacy policy - Licence Creative Commons