Study study type PathologyT1T0Patientssample sizesROB Results

endometrial cancer endometrial cancer

versus placebo plus SoC
atezolizumab plus SoC
AtTEnd, 2023
  NCT03603184
RCTendometrial canceratezolizumabplaceboWomen With Advanced/Recurrent Endometrial Cancer360 / 189NA
suggested
  • suggested 26 % decrease in progression or deaths (PFS)
Interim analysis of OS in all comers indicated a trend in favor for atezo, despite 45 (24.3%) placebo patients received immunotherapy as subsequent therapy. Second PFS and duration of response in the dMMR population confirmed the efficacy of atezo