Study study type PathologyT1T0Patientssample sizesROB Results

metastatic, hormone-sensitive prostate cancer metastatic, hormone-sensitive prostate cancer

versus androgen deprivation therapy (ADT)
docetaxel plus ADT
NCI E3805 (Scott), 2017
  NCT00309985
RCTmetastatic, hormone-sensitive prostate cancer397 / 393NA
conclusif
  • demonstrated 39 % decrease in deaths (OS) (PE)
STAMPEDE docetaxel, 2016
  NCT00268476
metastatic, hormone-sensitive prostate cancer-/-NA
suggested
  • suggested 22 % decrease in deaths (OS)
GETUG-AFU 15, 2013
  NCT00104715
RCTmetastatic, hormone-sensitive prostate cancerdocetaxel and androgen-deprivation therapy (ADT)androgen-deprivation therapy (ADT) alonepatients with metastatic non-castrate prostate cancer-/-NA
inconclusive
    no statistically significant result
CHAARTED unpublished
  NCT00268476
metastatic, hormone-sensitive prostate cancer-/-NA
suggested
  • suggested 28 % decrease in deaths (OS)