Study study type PathologyT1T0Patientssample sizesROB Results deaths (OS) Eprogression or deaths (PFS) ERFS/DFS E

mOC - L1 - all population metastatic/advanced OC (mOC) - 1st line (L1) mOC - L1 - all population

versus placebo plus SoC
atezolizumab plus SoC
IMagyn-050 (all population), 2021
  NCT03038100
RCTmOC - L1 - all populationatezolizumab plus paclitaxel carboplatin and bevacizumalbplaceb plus paclitaxel carboplatin and bevacizumalbpatients with stage III or stage IV epithelial ovarian, fallopian tube, or primaryperitoneal cancer with either macroscopic residual disease or who will undergo neoadjuvant chemotherapy followed by interval surgery651 / 650low
inconclusive -4% -8%

mOC - L1 - PDL1 positive metastatic/advanced OC (mOC) - 1st line (L1) mOC - L1 - PDL1 positive

versus placebo plus SoC
atezolizumab plus SoC
IMagyn-050 (PDL1 >1%), 2021
  NCT03038100
RCTmOC - L1 - PDL1 positiveatezolizumab plus paclitaxel carboplatin and bevacizumalbplaceb plus paclitaxel carboplatin and bevacizumalbpatients with stage III or stage IV epithelial ovarian, fallopian tube, or primaryperitoneal cancer with either macroscopic residual disease or who will undergo neoadjuvant therapy followed by interval surgery, PDL1 positive population391 / 393low
suggested -2% -20%