pembrolizumab alonetitledurvalumab plus tremelimumabtitleatezolizumab alonetitleatezolizumab plus cometinibtitleStandard of Care (SoC)titleBSCtitleregorafenibtitleKEYNOTE-177, 2020 NCT02563002 mCRC - 1st line (L1) 153/154IMblaze-370 (A ; all population), 2019 NCT02788279 mCRC - 2nd line (L2) 90/90IMblaze-370 (AC ; all population), 2019 NCT02788279 mCRC - 2nd line (L2) 183/90CO.26 study, 2020 NCT02870920 mCRC - 2nd line (L2) 119/61

Pathology:  mCRC - 1st line (L1);   mCRC - 2nd line (L2); 

mCRC - 1st line (L1)mCRC - 2nd line (L2)
KEYNOTE-177, 2020IMblaze-370 (A ; all population), 2019IMblaze-370 (AC ; all population), 2019CO.26 study, 2020
pembrolizumab alone1T1
durvalumab plus tremelimumab1T1
atezolizumab alone1T1
atezolizumab plus cometinib1T1
Standard of Care (SoC)0T0
BSC0T0
regorafenib0T0T0