• metastatic/advanced - colorectal cancer (mCRC)
• mCRC - 1st line (L1) 1
• mCRC - 2nd line (L2) 3
• endometrial cancer 1
• esophageal cancer (EC)

 

• immune chekpoint inhibitors
• anti-PD-(L)1
• pembrolizumab based treatment
• pembrolizumab alone

• versus all
• vs chemotherapy
• vs Standard of Care (SoC)

• study list
• mapping
• overview
• meta-analysis
• forest plot
• NMA
• excluded

Top evidence (RCT only, high risk of bias excluded) Best available evidence (possibly low or very low) All RCTs All studies (RCT+OBS)

Pathology:  mCRC - 1st line (L1);