abemaciclib plus endocrine therapytitleabemaciclib plus fulvestranttitleabemaciclib plus aromatase inhibitortitleendocrine therapytitlefulvestranttitlearomatase inhibitortitleMONARCH 3, 2017 NCT02246621 la/mBC - HR-positive - 1st line (L1) 328/165MonarchE, 2021 NCT03155997 la/mBC - HR-positive - 1st line (L1) 2808/2829MONARCH 2, 2020 NCT02107703 la/mBC - HR-positive - 2nd line (L2) 446/223

Pathology:  la/mBC - HR-positive - 1st line (L1);   la/mBC - HR-positive - 2nd line (L2); 

la/mBC - HR-positive - 1st line (L1)la/mBC - HR-positive - 2nd line (L2)
MONARCH 3, 2017MonarchE, 2021MONARCH 2, 2020
abemaciclib plus endocrine therapy1T1
abemaciclib plus fulvestrant1T1
abemaciclib plus aromatase inhibitor1T1
endocrine therapy0T0
fulvestrant0T0
aromatase inhibitor0T0