• metastatic/advanced - esophageal cancer (mEC)
• mEC - (neo)adjuvant (NA) 1
• mEC - 1st line (L1) 1
• mEC - 2nd line (L2) 3
• gastric or gastroesophageal junction cancer (GC)

 

• immune chekpoint inhibitors
• anti-PD-(L)1
• nivolumab based treatment
• nivolumab alone

• versus all
• vs non active control
• vs no additional treatment
• vs placebo

• study list
• mapping
• overview
• meta-analysis
• forest plot
• NMA
• excluded

Top evidence (RCT only, high risk of bias excluded) Best available evidence (possibly low or very low) All RCTs All studies (RCT+OBS)

Pathology:  mEC - (neo)adjuvant (NA);