graph Evidence gap map comparisons
antibody–drug conjugate
sacituzumab govitecan trastuzumab deruxtecan trastuzumab emtansine trastuzumab emtasine plus endocrine therapy
Comparator:  vs trastuzumab;   vs trastuzumab based treatment;   vs trastuzumab plus endocrine therapy;   vs trastuzumab emtansine;   vs lapatinib plus capecitabine;   vs Standard of Care (SoC);   vs chemotherapy; 
Risk of bias:  low;   some concerns;   high;  NA;