trastuzumab based treatment
docetaxel plus carboplatin with trastuzumab followed by trastuzumab doxorubicin plus cyclophosphamide followed by docetaxel plus trastuzumab
Comparator:  vs doxorubicin plus cyclophosphamide followed by docetaxel;   vs docetaxel plus carboplatin with trastuzumab followed by trastuzumab; 
Risk of bias:  low;   some concerns;   high;  NA;