graph Evidence gap map comparisons
atezolizumab based treatmentavelumab based treatmentnivolumab based treatmentpembrolizumab based treatmentImmune checkpoint association
atezolizumab alone atezolizumab plus bevacizumab avelumab plus axitinib nivolumab alone nivolumab plus cabozantinib pembrolizumab alone pembrolizumab plus axitinib pembrolizumab plus lenvatinib nivolumab plus ipilimumab
Comparator:  vs placebo;   vs nivolumab plus ipilimumab;   vs sunitinib;   vs everolimus; 
Risk of bias:  low;   some concerns;   high;  NA;