pembrolizumab plus SoC (n=-9) vs. placebo plus SoC (n=-9)
randomized controlled trial
pembrolizumab
pembrolizumab: 200mg Q3W for 6 cycles and chemotherapy: (carboplatin area under the curve [AUC] 5 or 6 paclitaxel 175 mg/m2 Q3W or carboplatin AUC 2 or 2.7 paclitaxel 60 mg/m2 QW) in stage 1 / pembrolizumab: 400mg Q6W for 6 cycles in stage 2
placebo
placebo and chemotherapy: (carboplatin area under the curve [AUC] 5 or 6 paclitaxel 175 mg/m2 Q3W or carboplatin AUC 2 or 2.7 paclitaxel 60 mg/m2 QW) in stage 1 / placebo in stage 2
Adjuvant Chemotherapy With or Without Radiotherapy