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proton pump inhibitors (PPI) in COVID-19 prophylaxis (excluding children) - Summary of results

OutcomeTE95% CInkI2ROBPub. bias conversion to SARS-CoV- 2–positive status via NP swabdetailed resultsBlanc, 2020 0.44 [0.23; 0.82] Ullah (COVID-19 Onset), 2020 1.53 [1.14; 2.05] 0.85[0.25; 2.88]Blanc, 2020, Ullah (COVID-19 Onset), 2020292%282NAnot evaluable new illness compatible with Covid-19 detailed resultsAlmario (Once daily), 2020 2.15 [1.90; 2.44] Almario (Twice daily), 2020 3.67 [2.93; 4.60] 2.79[1.65; 4.70]Almario (Once daily), 2020, Almario (Twice daily), 2020294%88,021seriousnot evaluable symptomatic Covid-19detailed resultsLee (COVID-19 onset), 2020 0.90 [0.79; 1.02] 0.90[0.79; 1.02]Lee (COVID-19 onset), 202010%27,746NAnot evaluable0.55.01.0relative treatment effectwww.metaEvidence.org2024-05-13 02:51 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 89 - treatments: 695 - roots T: 290

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