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control in COVID-19 prophylaxis (excluding children) - Summary of results

OutcomeTE95% CInkI2ROBPub. bias deathsdetailed resultsUKHSA report week 12 (24 March 2022), 2022 (REV) 2.22 [0.95; 5.17] 2.22[0.95; 5.17]UKHSA report week 12 (24 March 2022), 2022 (REV)10%NAnot evaluable deaths (time to event analysis only)detailed resultsUKHSA report week 12 (24 March 2022), 2022 (REV) 2.22 [0.95; 5.17] 2.22[0.95; 5.17]UKHSA report week 12 (24 March 2022), 2022 (REV)10%NAnot evaluable clinical deteriorationdetailed resultsLauring, 2022 (REV) 2.27 [1.94; 2.67] 2.27[1.94; 2.67]Lauring, 2022 (REV)10%11,690NAnot evaluable confirmed COVID (any severity)detailed resultsEngland (Andrews), 2021 (REV) 1.94 [1.32; 2.86] South Africa (Discovery Health, Collie), 2021 (REV) 2.00 [1.53; 2.62] Southern California (Tseng) - omicron, 2022 (REV) 1.44 [1.05; 1.96] Tenforde, 2022 (REV) 5.56 [4.33; 7.12] Thompson -VISIOn Network (omicron), 2022 (REV) 2.08 [1.84; 2.36] 2.32[1.51; 3.55]England (Andrews), 2021 (REV), South Africa (Discovery Health, Collie), 2021 (REV), Southern California (Tseng) - omicron, 2022 (REV), Tenforde, 2022 (REV), Thompson -VISIOn Network (omicron), 2022 (REV)593%138,105NAnot evaluable hospitalizationdetailed resultsLauring, 2022 (REV) 6.67 [5.44; 8.16] South Africa (Discovery Health, Collie), 2021 (REV) 3.33 [2.65; 4.19] Thompson -VISIOn Network (omicron), 2022 (REV) 5.26 [2.81; 9.85] 4.86[2.86; 8.26]Lauring, 2022 (REV), South Africa (Discovery Health, Collie), 2021 (REV), Thompson -VISIOn Network (omicron), 2022 (REV)390%11,690NAnot evaluable symptomatic Covid-19detailed resultsEngland (Andrews), 2021 (REV) 1.94 [1.32; 2.86] Kirsebom (UKHSA), 2022 (REV) 1.32 [1.26; 1.39] South Africa (Discovery Health, Collie), 2021 (REV) 2.00 [1.53; 2.62] Thompson -VISIOn Network (omicron), 2022 (REV) 2.08 [1.84; 2.36] 1.79[1.30; 2.44]England (Andrews), 2021 (REV), Kirsebom (UKHSA), 2022 (REV), South Africa (Discovery Health, Collie), 2021 (REV), Thompson -VISIOn Network (omicron), 2022 (REV)494%131,448NAnot evaluable0.510.01.0relative treatment effectwww.metaEvidence.org2024-05-12 15:03 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 89 - treatments: 649,650,589,651,968 - roots T: 290