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Vaxzevria (AstraZeneca Oxford - ChAdOx1 nCoV-19) in COVID-19 prophylaxis (excluding children) - Summary of results

OutcomeTE95% CInkI2ROBPub. bias confirmed COVID (any severity)detailed resultsKislaya, 2022 (REV) 2.78 [1.57; 4.93] Nguyen, 2022 (REV) 1.01 [0.90; 1.13] 1.61[0.60; 4.32]Kislaya, 2022 (REV), Nguyen, 2022 (REV)291%NAnot evaluable adverse eventsdetailed resultsCom-COV, 2021 1.14 [0.78; 1.66] Com-COV2, 2022 1.14 [0.82; 1.59] 1.14[0.89; 1.46]Com-COV, 2021, Com-COV2, 202220%1,535NAnot evaluable intracranial hemorrhage detailed resultsCom-COV, 2021 1.01 [0.02; 51.28] Com-COV2, 2022 4.97 [0.10; 251.14] 2.24[0.14; 35.97]Com-COV, 2021, Com-COV2, 202220%1,535NAnot evaluable ischemic strokedetailed resultsCom-COV, 2021 1.01 [0.02; 51.28] Com-COV2, 2022 2.48 [0.08; 74.26] 1.69[0.13; 22.07]Com-COV, 2021, Com-COV2, 202220%1,535NAnot evaluable Myocardial infarction detailed resultsCom-COV, 2021 1.01 [0.02; 51.28] Com-COV2, 2022 9.96 [0.33; 298.06] 3.74[0.29; 48.82]Com-COV, 2021, Com-COV2, 202220%1,535NAnot evaluable pulmonary embolismdetailed resultsCom-COV, 2021 1.01 [0.02; 51.28] Com-COV2, 2022 4.97 [0.10; 251.14] 2.24[0.14; 35.97]Com-COV, 2021, Com-COV2, 202220%1,535NAnot evaluable venous thromboembolism detailed resultsCom-COV2, 2022 2.48 [0.08; 74.26] 2.48[0.08; 74.26]Com-COV2, 202210%1,072NAnot evaluable0.55.01.0relative treatment effectwww.metaEvidence.org2024-09-27 15:47 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 89 - treatments: 759 - roots T: 290