studies

breast cancer - HR positive, buparlisib based treatment vs. all, meta-analysis of study results

OutcomeTE95% CInkI2ROBPub. bias deaths (OS)detailed resultsBELLE-2 (full population), 2017 0.87 [0.74; 1.02] BELLE-2 (patients with known PI3K status), 2017 0.91 [0.75; 1.10] 0.89[0.79; 1.00]BELLE-2 (full population), 2017, BELLE-2 (patients with known PI3K status), 201720%1,998lownot evaluable progression or deaths (PFS)detailed resultsBELLE-2 (full population), 2017 0.78 [0.68; 0.90] BELLE-2 (patients with known PI3K status), 2017 0.80 [0.68; 0.94] BELLE-2 (PI3K pathway activated), 2017 0.76 [0.60; 0.97] 0.78[0.71; 0.86]BELLE-2 (full population), 2017, BELLE-2 (patients with known PI3K status), 2017, BELLE-2 (PI3K pathway activated), 201730%2,370lownot evaluable objective responses (ORR)detailed resultsBELLE-2 (full population), 2017 1.60 [1.08; 2.39] BELLE-2 (patients with known PI3K status), 2017 1.47 [0.92; 2.34] BELLE-2 (PI3K pathway activated), 2017 1.34 [0.66; 2.71] 1.51[1.14; 1.99]BELLE-2 (full population), 2017, BELLE-2 (patients with known PI3K status), 2017, BELLE-2 (PI3K pathway activated), 201730%2,370lownot evaluable0.52.01.0relative treatment effectwww.metaEvidence.org2024-05-12 08:09 +02:00

TE: relative treatment effect (measured by a risk ratio, an odds ratio or an hazard ratio depending on what is reported in the papers); k: number of studies; n: total number of patients; ROB: risk of bias (ROB 2.0); Pub. bias: publication bias; OBS: observational studies; RCT: randomized clinical trials
studied treatment is better when TE > 1; studied treatment is better when TE < 1;

pathologies: 4,319,144,356,351,357,352,354,353,358,359 - treatments: 1430,1360,1431

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