Study		Exclusion reasons	Remarks	Reference(s)
Amaria, 2018	-	inadequate or absent control group		Amaria Nat. Med. 2018; 24:1649-1654 10.1038/s41591-018-0197-1
Blank, 2018	-	not relevant study design		Blank Nat. Med. 2018; 24:1655-1661 10.1038/s41591-018-0198-0
OpACIN-neo, 2019	-	not relevant outcome		Rozeman, E.A. The Lancet Oncology 2019; 20:948-. 10.1016/S1470-2045(19)30151-2