demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only
COVID 19 all comersCOVID-19 mild to moderateCOVID-19 severe or critically
COVID 19 hospitalizedCOVID 19 all comersCOVID-19 mild to moderateCOVID-19 severe or critically
Immunostimulants drugs
convalescent plasma treatment ConPlas-19 COPLA-II trial Bennett-Guerrero COP-COVID-19 NCT04403477 ... CONTAIN COVID-19 NCT04442191 ASCOT PERUCONPLASMA Co-CLARITY Baldeon PC/COVID-19 DAWN-Plasma RECOVERY ... NCT04528368 Menichetti NCT04397757 NCT04385199 Salman Holm K ConCOVID ... Kirenga CCAP-2 CONCOR-1 CONFIDENT LIFESAVER Libster CP-COVID-19 RECOVER Pouladzadeh Rasheed AlQahtani O’Donnell PlasmAr Sekine ... Li CAPSID REMAP-CAP ...
Early convalescent plasma. Balcells
immunoglobulin therapy Sakoulas Raman Tabarsi
interferon
IFN beta-1a SOLIDARITY ... Kalil ... Darazam ...
high-dose IFN beta-1a Darazam
IFN beta-1b Darazam ... Rahmani
inhaled interferon
IFN alpha
pegylated interferon-α2b Pandit Shashi Bhushan
recombinant super-compound interferon rSIFN-co Li
SNG001 inhaled interferon beta Synairgen SG016
interferon / TFF2 Fu
peginterferon Jagannathan
PNB001 Lattmann
neutralizing antibody ITAC
amubarvimab/romlusevimab (BRII-196 and BRII-198-Brii Biosciences) ACTIV-3 ...
bamlanivimab monotherapy ACTIV-3/TICO LY-CoV555
casirivimab/imdevimab (Ronapreve) RECOVERY ... Somersan-Karakaya ...
cilgavimab and tixagevimab (Evusheld) ACTIV-3/TICO ...
equine polyclonal antibodies INM005 Lopardo
sotrovimab (Xevudy; VIR-7831) ACTIV-3/ TICO ...

24 studies excluded by filtering options 0

4861 Cai -FAVIPIRAVIR, 2020 1310not a RCTrisk of bias not avaialble
5183 Qiong Zhou, 2020 0190selection pending
5275 ILBS-COVID-02 (Bajpai M), 2020 113high risk of bias
5406 Duan, 2020 1134not a RCThigh risk of bias
5446 Sean, 2020 1134not a RCThigh risk of bias
5534 Wang (early IFN), 2020 0134selection pending
5549 Hegerova, 2020 1134not a RCThigh risk of bias
5550 Abolghasemi, 2020 1134not a RCThigh risk of bias
5569 Dai W, 2020 2134excludednot a RCThigh risk of bias
5572 Hao, 2020 0200selection pending
5662 Salazar, 2020 1134not a RCThigh risk of bias
5698 PLACID, 2020 113high risk of bias
5717 PLACO-COVID, 2021 110risk of bias not avaialble
5719 CPC-SARS, 2021 113high risk of bias
5761 Joyner, 2020 1313not a RCThigh risk of bias
6140 Wang, 2020 0130selection pending
6159 Gemici, 2020 0130selection pending
6285 Gharebaghi, 2020 110risk of bias not avaialble
6341 PICP19 (Ray), 2020 113high risk of bias
6940 Bihariesingh-Sanchit (SuriCovid), 2021 1310not a RCTrisk of bias not avaialble
8243 Parikh, 2021 010selection pending
9112 LACCPT, 2021 110risk of bias not avaialble
9259 Ray, 2022 000selection pending
10178 Bargay-Lleonart, 2022 210excludedrisk of bias not avaialble