demonstrated suggested inconclusive safety concern ongoing study display ongoing demontrated benefit only
COVID 19 all comersCOVID-19 severe or critically
COVID 19 hospitalizedCOVID 19 all comersCOVID-19 severe or critically
anti-interleukin-6
Levilimab V.Lomakin ...
sarilumab CORIMUNO-SARI-1 ... sarilumab Sanofi phase 3 outside US
sarilumab high dose (400mg) Lescure ...
sarilumab low dose (200mg) Lescure ...
tocilizumab EU-CTR2020-001375-32 ... EU-CTR2020-001748-24 ... RCT-TCZ-COVID-19 Rutgers NCT04479358 ... NCT04434717 ... RECOVERY NCT04412772 ... EMPACTA Declercq J ... Dongsheng Wang Soin AS ... NCT04577534 ... BACC Bay Tocilizumab Trial REMAP-CAP ... Talaschian Veiga CORIMUNO-TOCI-ICU ... COVACTA ... Rosas ... MARIPOSA CORIMUNO-TOCI-1 ...

43 studies excluded by filtering options 0

5032 TOCOVID, 0 110risk of bias not avaialble
5123 Gritti et al., 2020 2300excludednot a RCTrisk of bias not avaialble
5444 TOCI-RAF Study Group (Campochiaro), 2020 1130not a RCTrisk of bias not avaialble
5449 Martinez-Sanz, 2020 1134not a RCThigh risk of bias
5489 Rojas-Marte, 2020 1134not a RCThigh risk of bias
5494 BREATH-19 Study, 0 2300excludednot a RCTrisk of bias not avaialble
5515 sarilumab Sanofi phase 3 US, 0 110risk of bias not avaialble
5522 Somers, 2020 1134not a RCThigh risk of bias
5524 HNF Hospital Tocilizumab multidisciplinary team, 2020 1134not a RCThigh risk of bias
5525 Capra, 2020 1134not a RCThigh risk of bias
5527 Colaneri, 2020 1134not a RCThigh risk of bias
5528 Mathilde, 2020 1134not a RCThigh risk of bias
5529 Andrew, 2020 1130not a RCTrisk of bias not avaialble
5554 Tsai, 2020 1133not a RCThigh risk of bias
5616 Biran, 2020 1133not a RCThigh risk of bias
5628 Rossotti, 2020 1134not a RCThigh risk of bias
5632 Holt, 2020 2130excludednot a RCTrisk of bias not avaialble
5633 ARI-RAF (Della-Torre), 2020 1130not a RCTrisk of bias not avaialble
5672 Klopfenstein, 2020 2134excludednot a RCThigh risk of bias
5796 SAM-COVID-19, 2020 0130selection pending
5805 Mikulska (tocilizumab plus methylprednisolone), 2020 0130selection pending
5941 Zeng, 2020 0300selection pending
5965 Pereira, 2020 0990selection pending
5966 Masia, 2020 0100selection pending
6281 Roumier, 2020 0100selection pending
6282 Menzella, 2020 0130selection pending
6335 Ruiz-Antoran, 2020 0130selection pending
6414 Mikulska, 2020 0130selection pending
6418 Guaraldi, 2020 0130selection pending
6420 Potere, 2020 0200selection pending
6425 Roumier, 2020 0130selection pending
6429 Kewan, 2020 0130selection pending
6431 Moreno-Pérez, 2020 0130selection pending
6433 Canziani, 2020 0200selection pending
6435 Gokhale, 2020 0130selection pending
6465 REMAP-CAP sarilumab, 2021 113high risk of bias
7007 Rashad, 2021 113high risk of bias
8156 Hamed, 2021 113high risk of bias
8509 Karampitsakos, 2021 0310selection pending
8960 NCT04377750 (HMO-0224-20), 0 113high risk of bias
9133 Karakike (ESCAPE), 2021 0310selection pending
9225 Belhassen-Garc??a, 2021 0110selection pending
9243 Sarhan, 2022 010selection pending