| breast cancer - adjuvant | breast cancer - HR positive | |||
| breast cancer - adjuvant | la/mBC - HR positive | la/mBC - HR-positive - 1st line (L1) | la/mBC - HR-positive - 2nd line (L2) | |
| palbociclib based treatment | ||||
| palbociclib | ||||
| palbociclib plus endocrine therapy | PENELOPE-B | PENELOPE-B | ||
| palbociclib plus fulvestrant | PALOMA-3 FLIPPER | |||
| palbociclib plus letrozole | ||||