Main treatments for test

deaths

Number of studies: k = 48
Number of treatments: n = 11
Number of pairwise comparisons: m = 48
Number of designs: d = 12

Fixed effects model

Treatment estimate (sm = 'OR', comparison: other treatments vs 'control'):
                                  OR           95%-CI
anti-interleukin-6            0.8006 [0.6387; 1.0036]
baricitinib plus remdesivir   0.5927 [0.3477; 1.0104]
colchicine                    0.3097 [0.0446; 2.1511]
control                            .                .
convalescent plasma treatment 0.7930 [0.4855; 1.2950]
corticosteroids               0.8810 [0.8061; 0.9628]
hydroxychloroquine            1.0630 [0.9611; 1.1758]
interferon                    1.1520 [0.9592; 1.3835]
lopinavir/ritonavir           1.0127 [0.9084; 1.1290]
remdesivir                    0.9119 [0.7904; 1.0519]
Vitamin D                     1.0461 [0.3736; 2.9296]

Random effects model

Treatment estimate (sm = 'OR', comparison: other treatments vs 'control'):
                                  OR           95%-CI
anti-interleukin-6            0.8006 [0.6387; 1.0036]
baricitinib plus remdesivir   0.5927 [0.3477; 1.0104]
colchicine                    0.3097 [0.0446; 2.1511]
control                            .                .
convalescent plasma treatment 0.7930 [0.4855; 1.2950]
corticosteroids               0.8810 [0.8061; 0.9628]
hydroxychloroquine            1.0630 [0.9611; 1.1758]
interferon                    1.1520 [0.9592; 1.3835]
lopinavir/ritonavir           1.0127 [0.9084; 1.1290]
remdesivir                    0.9119 [0.7904; 1.0519]
Vitamin D                     1.0461 [0.3736; 2.9296]

Quantifying heterogeneity / inconsistency:
tau^2 = 0; tau = 0; I^2 = 0% [0.0%; 0.0%]

Tests of heterogeneity (within designs) and inconsistency (between designs):
                    Q d.f. p-value
Total           24.08   38  0.9615
Within designs  20.58   36  0.9816
Between designs  3.50    2  0.1736

anti-interleukin-6 . . 0.80 (0.64; 1.00) . . . . . . .
1.35 (0.76; 2.41) baricitinib plus remdesivir . . . . . . . 0.65 (0.39; 1.09) .
2.59 (0.37; 18.20) 1.91 (0.26; 14.29) colchicine 0.31 (0.04; 2.15) . . . . . . .
0.80 (0.64; 1.00) 0.59 (0.35; 1.01) 0.31 (0.04; 2.15) control 1.26 (0.77; 2.06) 1.16 (1.06; 1.27) 0.91 (0.82; 1.01) 0.87 (0.72; 1.04) 0.99 (0.89; 1.10) 1.10 (0.95; 1.27) 0.96 (0.34; 2.68)
1.01 (0.59; 1.73) 0.75 (0.36; 1.54) 0.39 (0.05; 2.88) 1.26 (0.77; 2.06) convalescent plasma treatment . . . . . .
0.91 (0.71; 1.16) 0.67 (0.39; 1.16) 0.35 (0.05; 2.45) 1.14 (1.04; 1.24) 0.90 (0.55; 1.48) corticosteroids 1.08 (0.79; 1.47) . . . .
0.75 (0.59; 0.96) 0.56 (0.32; 0.96) 0.29 (0.04; 2.03) 0.94 (0.85; 1.04) 0.75 (0.45; 1.23) 0.83 (0.73; 0.94) hydroxychloroquine . 2.06 (0.07; 62.55) . .
0.69 (0.52; 0.93) 0.51 (0.29; 0.90) 0.27 (0.04; 1.88) 0.87 (0.72; 1.04) 0.69 (0.41; 1.16) 0.76 (0.62; 0.94) 0.92 (0.75; 1.14) interferon . . .
0.79 (0.62; 1.02) 0.59 (0.34; 1.01) 0.31 (0.04; 2.13) 0.99 (0.89; 1.10) 0.78 (0.47; 1.29) 0.87 (0.76; 1.00) 1.05 (0.91; 1.22) 1.14 (0.92; 1.41) lopinavir/ritonavir . .
0.88 (0.67; 1.15) 0.65 (0.39; 1.09) 0.34 (0.05; 2.37) 1.10 (0.95; 1.27) 0.87 (0.52; 1.45) 0.97 (0.82; 1.14) 1.17 (0.98; 1.39) 1.26 (1.00; 1.59) 1.11 (0.93; 1.33) remdesivir .
0.77 (0.27; 2.20) 0.57 (0.18; 1.81) 0.30 (0.03; 2.66) 0.96 (0.34; 2.68) 0.76 (0.24; 2.37) 0.84 (0.30; 2.37) 1.02 (0.36; 2.86) 1.10 (0.39; 3.13) 0.97 (0.34; 2.73) 0.87 (0.31; 2.47) Vitamin D